homozygosis การใช้

• Purging occurs because many deleterious alleles only express all their harmful effect in homozygosis.
• An autosomal dominant white has been also described in the wild canary which is lethal in homozygosis.
• It depends upon the " purging coefficient ", which represents the deleterious effects that are hidden in heterozygosis but exposed in homozygosis.
• This means that, when they occur in homozygosis ( double copies ), they reduce fitness by more than twice than when they occur in heterozygosis ( single copy ).
• This is illustrated in BOX 2 for the extreme case of inbreeding depression caused by recessive lethals, which are alleles that cause death before reproduction but only when they occur in homozygosis.
• Clearly, " genetic drift " has increased the overall level of homozygosis by the amount ( 0.6411-0.5342 ) = 0.1069 . In a complementary approach, the heterozygosity could be used instead.