isoprenaline การใช้

• Other antidotes for beta-blocker poisoning are salbutamol and isoprenaline.
• Its primary mechanism is direct stimulation of structural analogue of isoprenaline.
• In 1940 isoproterenol ( isoprenaline ) was discovered.
• The adverse effects of isoprenaline are also related to the drug's cardiovascular effects.
• Isoprenaline can produce tachycardia ( an elevated heart rate ), which predisposes patients to cardiac arrhythmias.
• Deaths have been reported following excessive use of isoprenaline inhalation preparations and the exact cause is unknown.
• Epinephrine ( adrenalin ) was the first of these, and next came isoprenaline ( isoproterenol ).
• "' Isoprenaline "'( TAAR1 agonist that is structurally similar to epinephrine ( adrenaline ).
• Isoprenaline has positive inotropic and chronotropic effects on the heart . ? 2 adrenoceptor stimulation in arteriolar smooth muscle induces vasodilation.
• By 1956 Riker had developed two MDI based products, the Medihaler-Ept containing epinephrine and the Medihaler-Iso containing Isoprenaline.
• Moderate stimulation ( intrinsic activities about half that of the reference standard, isoprenaline ) was observed in adipocytes from rat or hamster.
• Olodaterol is a nearly full ? 2 agonist, having 88 % intrinsic activity compared to the gold standard isoprenaline / isoproterenol ).
• In comparison, isoprenaline had a pD 2 = 8.29 and norepinephrine had pD 2 = 6.80 in human white fat cells.
• In the case of an abnormally slow heart rate ( bradyarrhythmias ), Atropine, catecholamines ( isoprenaline or salbutamol ), and / or temporary cardiac pacing can be used.
• Isoprenaline's effects on the cardiovascular system ( non-selective ) relate to its actions on cardiac ? 1 receptors and ? 2 receptors on smooth muscle within the tunica media of arterioles.
• In his famous work Ahlquist chose six agonists, including epinephrine, norepinephrine, ?-methyl noradrenaline and isoprenaline, and examined their effects on several organs, including blood vessels and the heart.
• In the first, from Lilly Research Laboratories, dichloroisoprenaline selectively blocked some smooth muscle inhibitory effects of adrenaline and isoprenaline; in the second, it blocked cardiac excitatory effects of adrenaline and isoprenaline as well.
• In the first, from Lilly Research Laboratories, dichloroisoprenaline selectively blocked some smooth muscle inhibitory effects of adrenaline and isoprenaline; in the second, it blocked cardiac excitatory effects of adrenaline and isoprenaline as well.
• Conversely inhibitors of the transport of noradrenaline into presynaptic axon terminals  cocaine being a prototype inhibitor  enhanced the effect of noradrenaline at ?-, but nor the effect of isoprenaline at ?-adrenoceptors.
• With the substituted phenethylamines it is a bit more vague seeing as this group includes many adrenergic receptor ligands like isoprenaline as well as what might be thought more " classic " substituted phenethylamines like 2C-B.