isoprenylation การใช้

• After translation, Ras goes through four steps of modification : isoprenylation, proteolysis, methylation and palmitoylation.
• Isoprenylation involves the enzyme farnesyltransferase ( FTase ) transferring a farnesyl group from farnesyl pyrophosphate ( FPP ) to the pre-Ras protein.
• Sometimes terpenoids are added to proteins, e . g ., to enhance their attachment to the cell membrane; this is known as isoprenylation.
• Post-translational modification of proteins can include : acetylation, acylation ( myristoylation, palmitoylation ), alkylation, arginylation, ADP-Ribosylation, biotinylation, formylation, geranylgeranylation, glutamylation, glycosylation, glycylation, hydroxylation, isoprenylation, lipoylation, methylation, nitroalkylation, phosphopantetheinylation, phosphorylation, prenylation, selenation, S-nitrosylation, succinylation, sulfation, transglutamination and ubiquitination ( sumoylation, neddylation ).