lipomatous การใช้
- Neocentromeres have been detected in human cancers, It has been observed that lipomatous tumors with alphoid sequences in the centromere are more aggressive and metastatic.
- It is also associated with congenital, lipomatous overgrowth of vascular malformations, epidermal nevi and skeletal / spinal anomalies ( CLOVES syndrome ) and fibroadipose hyperplasia ( FH ).
- Proposed etiologies include a variable form of neurofibromatosis, lipomatous degeneration, disturbed fetal circulation, trophic influence of a tumified nerve, in utero disturbance of growth-limiting factor or an error in segmentation.
- Particularly, these ring chromosomes involved in breakage-fusion-bridge cycles have a relatively high percentage of prevalence in lipomatous tumors and a lower but still notable prevalence in lung and acute myelogenous leukemia, according to the Mitelman Database.