mannosyltransferases การใช้

• POMT1 shares sequence similarity with protein O-mannosyltransferases of S . cerevisiae.
• Lipoarabinomannan is synthesized via addition of mannose residues to phosphoinositol by a series of mannosyltransferases to produce PIMs and lipomannan ( LM ).
• O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases.
• POMT2 encodes an integral membrane protein of the endoplasmic reticulum ( ER ) that shares significant sequence similarity with a family of protein O-mannosyltransferases of S . cerevisiae.