nitrosation การใช้

• Dimethylamine undergoes nitrosation under weak acid conditions to give dimethylnitrosamine.
• NNN is produced by the nitrosation of nornicotine during the curing, aging, processing, and smoking of tobacco.
• Two important biological reaction mechanisms of nitric oxide are S-nitrosation of thiols, and nitrosylation of transition metal ions.
• S-Nitrosation is a mechanism for dynamic, post-translational regulation of most or all major classes of protein.
• Nitration, nitrosation, azo coupling, halogenation, sulfonation, formylation, hydroxymethylation, and aminomethylation have been observed with substituted pyrimidines.
• S-nitrosation involves the ( reversible ) conversion of thiol groups, including cysteine residues in proteins, to form S-nitrosothiols ( RSNOs ).
• Modern practice is to add the oxime solution resulting from the nitrosation and the zinc dust gradually to a well-stirred solution of ethyl acetoacetate in glacial acetic acid.
• This animal carcinogen has been detected and quantified in human urine samples and it may also arise from nitrosation of dimethylamine by nitrogen oxides present in acid rain in highly industrialized countries.
• Nitrate or nitrite ( ingested ) under conditions that result in endogenous nitrosation has been classified as " probably carcinogenic to humans " by International Agency for Research on Cancer ( IARC ).
• The addition of a nitroso group to a sulfur atom of an amino acid residue of some protein is known as " S "-nitrosylation or " S "-nitrosation.
• Nitrate or "'nitrite "'( ingested ) under conditions that result in endogenous nitrosation has been classified as " " Probably carcinogenic to humans " " ( World Health Organization ( WHO ) of the United Nations.
• This process, known formally as " S "-nitrosation ( and referred to by many in the field as " S "-nitrosylation ), has been shown to reversibly inhibit NOS3 activity in vascular endothelial cells.
• Hemoglobin is a prominent example of a heme protein that may be modified by 種O by both pathways : 種O may attach directly to the heme in the nitrosylation reaction, and independently form S-nitrosothiols by S-nitrosation of the thiol moieties.
• Hemoglobin is a prominent example of a heme protein that may be modified by NO by both pathways : NO may attach directly to the heme in the nitrosylation reaction, and independently form S-nitrosothiols by S-nitrosation of the thiol moieties.