pentoxifylline การใช้

• Co-administration of pentoxifylline and thiopental causes death by acute pulmonary edema in rats.
• It is a metabolite of pentoxifylline.
• Co-administration of pentoxifylline and sodium thiopental may cause death by acute pulmonary edema in rats.
• Other agents that have been investigated for use in treatment of HRS include pentoxifylline, and misoprostol.
• These include potassium para-aminobenzoate ( Potaba ), pentoxifylline ( acting through TGF?1 inhibition ), and Coenzyme Q10.
• Other topical agents such as amitriptyline, gabapentin, Citrullus colocynthis extract, nifedipine, and pentoxifylline are also under investigation.
• Contraindications include intolerance to pentoxifylline or other xanthine derivatives, recent retinal or cerebral haemorrhage, and risk factors for haemorrhage.
• Corticosteroid therapy or pentoxifylline have been used with mixed results for patients whose increased mortality is indicated with a value greater than 32.
• While most clinically useful TNF inhibitors are monoclonal antibodies, some are simple molecules such as xanthine derivatives ( e . g . pentoxifylline ) and bupropion.
• Pentoxifylline has been used successfully to treat acute disease although its use is greatly limited by its gastrointestinal toxicity ( mostly nausea, vomiting, and diarrhea ).
• "' Pentoxifylline "'( AAN ) is a xanthine derivative used as a drug to treat muscle pain in people with peripheral artery disease.
• The evidence for all of these therapies is based on either case series, or in the case of pentoxifylline, extrapolated from a subset of patients treated for alcoholic hepatitis.
• In addition, using of a PDE inhibitor ( pentoxifylline ) in pentylenetetrazole-induced seizure indicated the antiepileptic effect by increasing the time latency to seizure incidence and decreasing the seizure duration in vivo.
• Angiotensin converting enzyme inhibitors, beta-blockers, antiplatelet agents ( aspirin and clopidogrel ), naftidrofuryl, pentoxifylline, and cilostazol ( selective PDE3 inhibitor ) are used for the treatment of intermittent claudication.
• Compounds that have been found to inhibit AGE formation in the laboratory include Vitamin C, benfotiamine, pyridoxamine, alpha-lipoic acid, taurine, pimagedine, aspirin, carnosine, metformin, pioglitazone, and pentoxifylline.
• Methylated xanthines ( methylxanthines ), which include caffeine, aminophylline, IBMX, paraxanthine, pentoxifylline, theobromine, and theophylline, affect not only the airways but stimulate heart rate, force of contraction, and cardiac arrhythmias at high concentrations.
• Numerous other adjuvant therapies have been tried in TEN including, corticosteroids, cyclosporin, cyclophosphamide, plasmapheresis, pentoxifylline, N-acetylcysteine, ulinastatin, infliximab, and Granulocyte colony-stimulating factors ( if TEN associated-leukopenia exists ).
• This may include flunixin meglumine ); intravenous dimethyl sulfoxide; administration of products such as Biosponge or activated charcoal via nasogastric tube to bind endotoxins; polymyxin B or plasma for endotoxemia; supportive shoeing; low doses of intramuscular acepromazine; and pentoxifylline.
• Available treatment options include pentoxifylline ( PTX ), which is a nonspecific TNF inhibitor, corticosteroids, such as prednisone or prednisolone ( CS ), corticosteroids with "-acetylcysteine ( CS with NAC ), and corticosteroids with pentoxifylline ( CS with PTX ).
• Available treatment options include pentoxifylline ( PTX ), which is a nonspecific TNF inhibitor, corticosteroids, such as prednisone or prednisolone ( CS ), corticosteroids with "-acetylcysteine ( CS with NAC ), and corticosteroids with pentoxifylline ( CS with PTX ).