photosensitizers การใช้

• Metal-free organic complexes have also been successfully employed as photosensitizers.
• CdSe nanocrystals are efficient triplet photosensitizers.
• Photodynamic therapy ( PDT ) with several photosensitizers is a promising modality for the treatment of cancer.
• This method of integrating photosensitizers into protein crystals has provided a powerful new tool for studying biochemical reaction dynamics.
• So companies in the United States, Canada, Japan and England are hunting better photosensitizers _ and other targets.
• The photosensitizers are excited from the ground state ( S ) to the excited state ( S  " ).
• However, this PDT treatment results in serious side effects because non-targeted photosensitizers are also taken up by normal tissues.
• Some essential oils, including many of the citrus peel oils, are photosensitizers, increasing the skin's vulnerability to sunlight.
• Photosensitizers are molecules that rapidly destroy cells though the production of reactive oxygen species ( ROS ) when exposed to light at specific wavelength.
• Bio-inspired manganese clusters have been shown to possess water oxidation activity when adsorbed on clays together with ruthenium photosensitizers, although with low turnover numbers.
• The key to making light therapy work was injecting photosensitizers that concentrate in diseased cells but quickly clear out of normal cells _ and then harnessing the right wavelength of light.
• Multiple treatment regimens using different photosensitizers, incubation times, light sources, and pretreatment regimens have been studied and suggest that longer incubation times lead to higher rates of lesion clearance.
• In recent years, chemical tags have been tailored to advanced imaging technologies more so than fluorescent proteins due to the fact that chemical tags can localize photosensitizers closer to the target proteins.
• Photosensitizers commercially available for clinical use include Allumera, Photofrin, Visudyne, Levulan, Foscan, Metvix, Hexvix, Cysview and Laserphyrin, with others in development, e . g.
• Even though the new mAb-based photosensitizers are distributed throughout the body, it can be activated by light for targeted PIT only when bound to specific proteins on cancer cellular membrane.
• The process uses one of two supramolecular assemblies based on Co ( II )-templated coordination of Ru ( bpy ) 32 + ( bpy = 2, 22-bipyridyl ) analogues as photosensitizers and electron donors to a cobaloxime macrocycle.
• But with recent advances in laser fiber optics and photosensitizers, " we're seeing a resurgence in interest, " said George Washington University's Dr . Michael Manyak, who has had success in bladder cancer and is now studying infertility-causing endometriosis.