promegestone การใช้

• The 19-norprogesterone derivatives demegestone, promegestone, and trimegestone are also derivatives of 17?-methylprogesterone ( see below ).
• "' Promegestone "'( albumin; it does not bind to sex hormone-binding globulin, and binds only weakly to transcortin.
• Trimegestone is closely related structurally to the 19-norprogesterone and 17?-methylprogesterone derivatives demegestone and promegestone and is also known as "'21-hydroxypromegestone " '.
• 19-Norprogesterone is the parent compound of a group of medically used progestins, which includes nomegestrol acetate, promegestone, trimegestone, demegestone, gestonorone caproate, segesterone acetate ( nestorone ), and norgestomet ( veterinary ).
• They can be categorized into several structural groups, including derivatives of retroprogesterone, 17?-hydroxyprogesterone, 17?-methylprogesterone, and 19-norprogesterone, with a respective example from each group including dydrogesterone, medroxyprogesterone acetate, medrogestone, and promegestone.
• "' 19-Norpregnane "', also known as "'13?-methyl-17?-ethylgonane "', is a norsteroid and the 19-demethyl derivatives of it such as the progestins demegestone, gestonorone caproate ( gestronol hexanoate ), nomegestrol acetate, norgestomet, promegestone, segesterone acetate ( nestorone ), and trimegestone.