selectin การใช้

• The selectins and selectin ligands determine the organ selectivity of metastasis.
• Shear forces are also found to affect E-selectin expression.
• E-selectin ligands also play a role in cancer metastasis.
• Traditional Chinese herbal medicines, like berberine downregulate E-selectin.
• P-selectin expression is induced by two distinct mechanisms.
• Both CD44 and L-selectin have been implicated in leukocyte trafficking.
• The alpha granules express the adhesion molecule P-selectin and CD63.
• They carry carbohydrates in order to be recognized by L-selectin.
• The functional capacity of selectin is limited to leukocyte collaborations with vascular endothelium.
• The functions of the EGF-like domain vary between different selectin types.
• Another test was for E-selectin, a molecule whose levels indicate inflammation.
• Neutrophils and eosinophils bind to E-selectin.
• It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups.
• This indicates that sulfatide may serve as a specific ligand for P-selectin.
• The purple cloud is selectin, a protein that plays a key role in inflammation.
• Similar results occurred for E-selectin.
• Sialic acid-rich glycoproteins ( sialoglycoproteins ) bind selectin in humans and other organisms.
• Each selectin has a carbohydrate recognition domain that mediates binding to specific glycans on apposing cells.
• P-selectin has a functional role in metastasis of tumor similar to E-selectin.
• P-selectin has a functional role in metastasis of tumor similar to E-selectin.