tfiid การใช้
- This gene encodes a small subunit associated with a subset of TFIID complexes.
- This gene encodes a subunit of TFIID present in a subset of TFIID complexes.
- This gene encodes a subunit of TFIID present in a subset of TFIID complexes.
- This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex.
- This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11.
- This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes.
- This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes.
- Some of these associated factors are weakly attached, whereas others are tightly associated with TBP in the TFIID complex.
- TFIID is composed of the TATA-binding protein ( TBP ) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs.
- One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
- TFIID is composed of the polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases.
- The mediator of RNA polymerase II transcription subunit 1 protein is a subunit of the CRSP ( cofactor required for TFIID, is required for efficient activation by SP1.
- This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex.
- This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex.
- TFIID and human mediator coactivator ( THRAP3 ) complexes ( mediator complex, plus THRAP3 protein ) assemble cooperatively on promoter DNA, from which they become part of the RNAPII holoenzyme.
- The protein encoded by this gene is a subunit of the CRSP ( cofactor required for SP1 activation ) complex, which, along with TFIID, is required for efficient activation by SP1.
- The TATA box is usually found at the binding site of RNA polymerase II . TFIID, a transcription factor, binds to the TATA box, followed by TFIIA binding to the upstream part of the TFIID protein.
- The TATA box is usually found at the binding site of RNA polymerase II . TFIID, a transcription factor, binds to the TATA box, followed by TFIIA binding to the upstream part of the TFIID protein.
- However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity . [ supplied by OMIM]
- The most common GTFs are TFIIA, TFIIB, TFIID ( see also TATA binding protein ), TFIIE, TFIIF, and TFIIH . The preinitiation complex binds to promoter regions of DNA upstream to the gene that they regulate.
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