thioamide การใช้

• TPO is inhibited by the thioamide drugs, such as propylthiouracil and methimazole.
• With amides the reaction product is a thioamide.
• It is the thioamide derivative of diazepam.
• The compound consists of a 1, 2, 4-triazole heterocycle with three functional groups : amine, thioamide, hydrazide.
• To obtain the amidine linkage, a tripeptide intermediate was coupled to a phthaloyl-protected thioamide via mercury-mediated condensation using mercury ( II ) trifluoromethanesulfonate ( Hg ( OTf ) 2 ) to yield a branched amidine intermediate.