thrombasthenias การใช้

• Thrombasthenia of Glanzmann and Naegeli ( Glanzmann thrombasthenia ) is extremely rare.
• Thrombasthenia of Glanzmann and Naegeli ( Glanzmann thrombasthenia ) is extremely rare.
• In contrast, glycoproteinIb receptors are normal with Glanzmann's thrombasthenia.
• Deficiency in the IIb / IIIa complex is described as Glanzmann's thrombasthenia.
• Thus, failure to retract can be a sign of thrombocytopenia or a rare condition called thrombasthenia.
• "' Leukocyte adhesion deficiency "'( LAD ), is a rare Glanzmann thrombasthenia-like bleeding tendency.
• The bleeding tendency in Glanzmann's thrombasthenia is variable, Unidentified factors other than the platelet defect itself may have important roles.
• Other indications include use for patients with acquired hemophilia, people born with a deficiency of factor VII, and people with Glanzmann's thrombasthenia.
• Understanding of the role of GpIIb / IIIa in Glanzmann's thrombasthenia led to the development of GpIIb / IIIa inhibitors, a class of powerful antiplatelet agents.
• The prevention of the beta-3 activation is specifically related to LAD-3, causing Glanzmann's thrombasthenia symptoms, a condition in which patients bleed excessively.
• An abnormality or disease of the platelets is called a thrombocytopathy, which can be either a low number of platelets ( thrombocytopenia ), a decrease in function of platelets ( thrombasthenia ), or an increase in the number of platelets ( thrombocytosis ).