transactivator การใช้

• The latter may operate via the FOXO1 transactivator.
• The MetR protein is required for MetE and MetH gene expression and functions as a transactivator of transcription for these genes.
• Haseltine and his laboratory discovered that HTLV carried a novel gene, called the transactivator X ( now called " tax " ).
• This study also provided the first example of an in vitro transcription system that responds to regulatory events acting upstream of the binding of a transactivator.
• The function of the protein coded for by gene X is not fully understood, but some evidence suggests that it may function as a transcriptional transactivator.
• Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element ( TAR ) located downstream of the transcription initiation site.
• These proteins with RNA polymerase II, assemble into complexes that are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site.
• What's the difference between a transactivator and an ( upregulating ) transcription factor ?-- Potato Business "'18 : 28, 1 September 2007 ( UTC)
• In HTLV-1 myelopathy, Tax, transactivator expressed by HTLV-1, interacts with ?-internexin in cell culture resulting in dramatic reduction in Tax transcactivation and intermediate filament formation.
• Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression.
• Approximately 20 of these proteins have been found in the mammalian genome and include two major subfamilies called NODs and NALPs, the MHC Class II transactivator ( CIITA ), IPAF, BIRC1, and other molecules.
• The difference between Tet-On and Tet-Off is not whether the transactivator turns a gene on or off, as the name might suggest; rather, both proteins "'activate "'expression.
• In response to interferon ( IFN ), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 ( IRF9 ), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly.
• The Haseltine laboratory discovered a novel transacting protein, they named the transactivator " tat ", and a second protein, originally named " art " now called " rev ", both required for virus replication.
• The entirety of several TetO sequences with a minimal promoter is called a " tetracycline response element ( TRE ) ", because it responds to binding of the tetracycline transactivator protein tTA by increased expression of the gene or genes downstream of its promoter.
• Activation of HIV-1 gene expression by the transactivator " Tat " is dependent on an RNA regulatory element ( TAR ) located " downstream " ( i . e . to-be transcribed at a later point in time ) of the transcription initiation site.
• The Tet-Off system makes use of the " tetracycline transactivator ( tTA ) " protein, which is created by fusing one protein, TetR ( tetracycline repressor ), found in " Escherichia coli " bacteria, with the activation domain of another protein, VP16, found in the Herpes Simplex Virus.
• The basic difference is that a " transcription factor " usually descibes an endogenous protein whereas a " transactivator " is a term that can mean anything that activates genes in trans, including upregulating transcription factors that are both endogenous and exogenous ( such as viral in origin ) . t 19 : 36, 1 September 2007 ( UTC)