uricase การใช้

• Alkalization is also not required if uricase is used.
• Allantoin is a major metabolic intermediate in most organisms including animals, plants and bacteria and is produced as a degradation product of purine nucleobases by urate oxidase ( or uricase ) from uric acid.
• In contrast to rasburicase, pegloticase is pegylated to increase its elimination half-life from about eight hours to ten or twelve days, and to decrease the immunogenicity of the foreign uricase protein.
• In legumes, 2 forms of uricase are found : in the roots, the tetrameric form; and, in the uninfected cells of root nodules, a monomeric form, which plays an important role in nitrogen-fixation.
• ""'Streptomyces rochei " "'is a bacterium species from the genus of " Streptomyces " which has been isolated from soil in Russia . " Streptomyces rochei " produces borrelidin, butyrolactol A, butyrolactol B, uricase and streptothricin . " Streptomyces rochei " has antifungal activity against Fusarium oxysporum f . sp . lycopersici and Aspergillus fumigatus.