allosteric การใช้

• Direct thrombin inhibitors provides an excellent example of negative allosteric modulation.
• For example, allosteric inhibitors may display competitive, uncompetitive inhibition.
• More recently, the " good example of allosteric regulation.
• ADP is the key allosteric inhibitor of ribose-phosphate diphosphokinase.
• A positive ago-allosteric modulator increases both efficacy and potency.
• In this way, allosteric interactions can either inhibit or activate enzymes.
• The activity of many enzymes is regulated by allosteric effectors.
• Most allosteric effects can be explained by the " concerted"
• Therefore, greater GPCR selectivity may be obtained by targeting allosteric sites.
• Strictly speaking the relationship between IR and ligand shows complex allosteric properties.
• Oxiracetam acts also as a positive allosteric modulator of the AMPA receptors.
• Methylphenylpiracetam is a positive allosteric modulator of the sigma-1 receptor.
• Allosteric enzymes are generally larger in mass than other enzymes.
• CTP is also subject to various forms of allosteric regulation.
• The reaction product CTP also serves as an allosteric inhibitor.
• Allosteric enzymes are usually under the simultaneous control of several allosteric effectors.
• Allosteric enzymes are usually under the simultaneous control of several allosteric effectors.
• These simple molecular mechanisms account for the integrative properties of allosteric enzymes.
• This protein may use the morpheein model of allosteric regulation.
• Interconversion of morpheein forms can be a structural basis for allosteric regulation.