centrosomes การใช้

• The two centrioles in the centrosome are tied to one another.
• The maintenance of astral microtubules is dependent on the integrity of centrosome.
• During mitosis, the protein associates with spindle microtubules near the centrosomes.
• In early mitosis, several motor proteins drive the separation of centrosomes.
• Second, the centrosomes are separated via microtubules motor proteins.
• The encoded protein usually remains with the mother centrosome after centrosomal duplication.
• They are organized into radial arrays around the centrosomes.
• The protein appears to associate with the centrosome complex during the cell cycle.
• During mitosis, the protein is associated with the centrosomes and spindle microtubules.
• CEP350 is required to anchor microtubules at the centrosome.
• The gene product is also associated with centrosome maturation.
• Centrosomes are the major microtubule organizing center ( MTOC ) in mammalian cells.
• The centrosome cycle consists of four phases that are synchronized to cell cycle.
• Centrosome duplication is heavily regulated by cell cycle controls.
• The role of centrosomes in tumor progression is unclear.
• Then NPM is released from binding to an unduplicated centrosome, thereby triggering duplication.
• Plant cells lack centrosomes as microtubule organizing centers.
• Aneuploidy and tumorigenesis can also result from centrosome abnormality, particularly centrosome amplification defects.
• Aneuploidy and tumorigenesis can also result from centrosome abnormality, particularly centrosome amplification defects.
• Centrosome duplication and maturation regulated by Plk1 occurs from late S phase to prophase.