centrosomes การใช้
- The two centrioles in the centrosome are tied to one another.
- The maintenance of astral microtubules is dependent on the integrity of centrosome.
- During mitosis, the protein associates with spindle microtubules near the centrosomes.
- In early mitosis, several motor proteins drive the separation of centrosomes.
- Second, the centrosomes are separated via microtubules motor proteins.
- The encoded protein usually remains with the mother centrosome after centrosomal duplication.
- They are organized into radial arrays around the centrosomes.
- The protein appears to associate with the centrosome complex during the cell cycle.
- During mitosis, the protein is associated with the centrosomes and spindle microtubules.
- CEP350 is required to anchor microtubules at the centrosome.
- The gene product is also associated with centrosome maturation.
- Centrosomes are the major microtubule organizing center ( MTOC ) in mammalian cells.
- The centrosome cycle consists of four phases that are synchronized to cell cycle.
- Centrosome duplication is heavily regulated by cell cycle controls.
- The role of centrosomes in tumor progression is unclear.
- Then NPM is released from binding to an unduplicated centrosome, thereby triggering duplication.
- Plant cells lack centrosomes as microtubule organizing centers.
- Aneuploidy and tumorigenesis can also result from centrosome abnormality, particularly centrosome amplification defects.
- Aneuploidy and tumorigenesis can also result from centrosome abnormality, particularly centrosome amplification defects.
- Centrosome duplication and maturation regulated by Plk1 occurs from late S phase to prophase.
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