cytopenia การใช้

• The investigation of fostamatinib began with studies involving the treatment of mouse models with cytopenia.
• Although autoimmune symptoms do not feature prominently in XMEN autoimmune cytopenias were observed in two unrelated patients.
• This system takes into account the percentage of blasts in the marrow, cytogenetics, and number of cytopenias.
• Another sign is autoimmune cytopenias and polyclonal hypergammaglobulinemia and a family history of ALPS or non-malignant lymphoproliferation.
• Therefore, HLH should be included in the differential diagnosis of ICU ( Intensive Care Unit ) patients with cytopenia and hyperferritinemia.
• The features generally used to define a MDS are : blood cytopenias; ineffective hematopoiesis; dyserythropoiesis; dysgranulopoiesis; dysmegakaropoiesis and increased myeloblasts.
• More rarely, allopurinol can also result in the depression of bone marrow elements, leading to cytopenias, as well as aplastic anemia.
• Hemophagocytosis is a clinical condition, found in many infectious and inflammatory disorders, where activated macrophages have engulfed apparently viable blood cells, resulting in reduced white or red cell count ( cytopenia ).
• APG101 is in a phase I trial to treat patients with MDS . MDS is a disease in which the bone marrow does not make enough healthy blood cells, which leads to blood cytopenias, especially anemia.
• Germline gain-of-function ( GOF ) mutations in the gene " STAT3 " causes this early-onset autoimmune disease characterized by lymphadenopathy, autoimmune cytopenias, multiorgan autoimmunity, infections, eczema, and short stature.