desmethyldiazepam การใช้

• Desmethyldiazepam is responsible for most of the therapeutic effects of clorazepate.
• It is metabolised into diazepam, desmethyldiazepam and oxydiazepam.
• Clorazepate is a prodrug for desmethyldiazepam, which is rapidly produced as an active metabolite.
• Prazepam is a prodrug for desmethyldiazepam which is responsible for the therapeutic effects of prazepam.
• The main active metabolite of diazepam is desmethyldiazepam ( also known as nordazepam or nordiazepam ).
• It is a prodrug for desmethyldiazepam.
• The main active metabolites of pinazepam are depropargylpinazepam ( " N "-desmethyldiazepam, nordazepam ) and oxazepam.
• The main pharmacological effects of fosazepam may be due to its metabolite nordiazepam ( desmethyldiazepam ), rather than the parent drug.
• Diazepam has a biphasic half-life of about one to three days, and two to seven days for the active metabolite desmethyldiazepam.
• "' Delorazepam "'also known as "'chlordesmethyldiazepam "'and Nordiclazepam is a drug which is a benzodiazepine and a derivative of desmethyldiazepam.
• Pinazepam and its metabolite " N "-desmethyldiazepam are transferred to the developing fetus " in utero ", but the plasma drug level in the mother is usually significantly higher than in the fetus.