isoproterenol การใช้

• Until about a year ago, two companies made isoproterenol.
• In symptomatic cases, intravenous atropine or isoproterenol may transiently improve conduction.
• In 1940 isoproterenol ( isoprenaline ) was discovered.
• In 1949 isoproterenol was used generally to treat asthma patients, given sublingually or inhaled.
• Epinephrine ( adrenalin ) was the first of these, and next came isoprenaline ( isoproterenol ).
• These cells are also sensitive to lipogenic and lipolytic hormones and drugs, including epinephrine, isoproterenol, and insulin.
• Rhonda Luniak, a spokeswoman, said Abbott could no longer get some of the raw chemicals that go into isoproterenol.
• Endogenous sulfur dioxide also diminishes myocardial damage, caused by isoproterenol adrenergic hyperstimulation, and strengthens the myocardial antioxidant defense reserve.
• Rarely, drugs such as iodides, phenylbutazone, thiouracil, isoproterenol, heavy metals, sulfisoxazole, and phenothiazines cause parotid swelling.
• Olodaterol is a nearly full ? 2 agonist, having 88 % intrinsic activity compared to the gold standard isoprenaline / isoproterenol ).
• "Isoproterenol is a drug that saves people lives, " said William A . Gouveia, pharmacy director at the New England Medical Center.
• The first patient package insert required by the FDA was in 1968, mandating that isoproterenol inhalation medication must contain a short warning that excessive use could cause breathing difficulties.
• Activation of the LysRS-Ap 4 A-MITF signaling pathway by isoproterenol has been confirmed in cardiomyocytes, where MITF is a major regulator of cardiac growth and hypertrophy.
• Other critical drugs in short supply include tetanus-diphtheria toxoid vaccine and the injectable form of isoproterenol, which many hospitals keep on the " crash carts " used to treat patients who go into cardiac arrest.
• The MMRL named this the Brugada syndrome in 1996, after Josep and Pedro Brugada, who first described this as a new clinical entity in 1992, and in 1999 proposed use of quinidine and isoproterenol for its treatment.
• Van Metre, an allergist, also helped change the way doctors treated asthmatics when he observed that the doses of steroids used to help asthmatic children were inhibiting their growth and that excessive use of a bronchodilator, isoproterenol, could be harmful.
• Four of the 14 subjects without chronic fatigue syndrome also tested positive, but only in the second and third stages, in which the subjects were injected with increasing amounts of isoproterenol ( Isuprel ), a drug that resembles epinephrine, or adrenaline.
• Several factors inhibit this process including increased cardiac output, hypocapnia, hypothermia, acidosis / alkalosis, increased pulmonary vascular resistance, inhaled anesthetics, calcium channel blockers, positive end-expiratory pressure ( PEEP ), high-frequency ventilation ( HFV ), isoproterenol, nitric oxide, and vasodilators.
• In a transgenic mouse model of cardiac-specific overexpression of CARP, mice exhibited normal physiology at baseline, but were protected against pathological cardiac hypertrophy induced via pressure-overload or isoproterenol, which could be attributed to the downregulation of the ERK1 / 2, MEK and TGFbeta-1 pathways.
• NF-?B is important in regulating cellular responses because it belongs to the category of " rapid-acting " primary transcription factors, i . e ., transcription factors that are present in cells in an inactive state and do not require new protein synthesis in order to become activated ( other members of this family include transcription factors such as c-Jun, isoproterenol, cocaine, and ionizing radiation.