oncocytoma การใช้

• Gross appearance of the cut surface of a nephrectomy specimen containing a "'renal oncocytoma " '.
• ARPP has also been shown to be a potentially useful biomarker for the differential diagnosis between oncocytoma and chromophobe renal cell carcinomas.
• An "'oncocytoma "'is a tumor made up of oncocytes, epithelial cells characterized by an excessive amount of mitochondria, resulting in an abundant acidophilic, granular cytoplasm.
• The main differential diagnosis of renal oncocytoma is " chromophobe renal cell carcinoma oncocytic variant ", which like the renal oncocytoma has eosinophilic cytoplasm, but has perinuclear clearing and, typically, some degree of nuclear atypia.
• The main differential diagnosis of renal oncocytoma is " chromophobe renal cell carcinoma oncocytic variant ", which like the renal oncocytoma has eosinophilic cytoplasm, but has perinuclear clearing and, typically, some degree of nuclear atypia.
• This loss of heterozygosity is a common mechanism in cancer, and it is frequently detected in the renal cancers associated with BHD . The molecular genetic defects in renal tumors of people with BHD are different from two other similar kidney tumors, chromophobe renal cell carcinoma and renal oncocytoma.
• Genetic testing should be considered with adrenocortical carcinoma; carcinoid tumors; diffuse gastric cancer; fallopian tube / primary peritoneal cancer; leiomyosarcoma; medullary thyroid cancer; paraganglioma / pheochromocytoma; renal cell carcinoma of chromophobe, hybrid oncocytic, or oncocytoma histology; sebaceous carcinoma; and sex cord tumors with annular tubules.