opsonisation การใช้

• The TEP1 cascade most closely resembles the alternative pathway as insects do not possess amplification loops to increase pathogen opsonisation.
• However, cell opsonisation by antibody leads normally to phagocytosis of the labeled cells, as seen in the case of HIV.
• Possible class effects of antibodies include : Opsonisation, agglutination, haemolysis, complement activation, mast cell degranulation, and neutralisation ( though this class effect may be mediated by the Fab region rather than the Fc region ).
• "Opsonization " ( also, opsonisation ) is the molecular mechanism whereby molecules, microbes, or apoptotic cells are chemically modified to have stronger interactions with-to be more " delicious " to-cell surface receptors on phagocytes and NK cells.
• T cells that express the T cell receptor which recognizes the antigen-MHCII complex ( with co-stimulatory factors-CD40 and CD40L ) cause the B-cell to produce antibodies that help opsonisation of the antigen so that the bacteria can be better cleared by phagocytes.
• Since C3 convertases cleave C3 to produce C3b which can then form an additional C3 convertase through the alternative pathway, this is a potential mechanism of signal amplification in the complement cascade resulting in the deposition of large numbers of C3b molecules on the surface of activating particles, enabling opsonisation and acute local inflammation.