predentin การใช้

• Newly secreted dentin is unmineralised and is called predentin.
• The differentiation phase of the Induction stage is initiated by the presence of newly formed predentin.
• As odontoblasts deposit organic matrix termed predentin, they migrate toward the center of the dental papilla.
• Later, new areas of mineralization occur as globules form in the partially mineralized predentin during the secondary mineralization phase.
• The ameloblasts will only become fully functional after the first layer of dentin ( predentin ) has been formed by odontoblasts.
• In these areas, only primary mineralization has occurred within the predentin, and the globules of dentin do not fuse completely.
• Maturation of dentin or mineralization of predentin occurs soon after its apposition, which takes place two phases : primary and secondary.
• Initially, the calcium hydroxyapatite crystals form as globules, or calcospherules, in the collagen fibers of the predentin, which allows for both the expansion and fusion during the primary mineralization phase.